# High blood pressure by Dr. #
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* In 2017, Cardiovascular Diseases, Heart
* A medicine against high blood pressure
* Spray against high blood pressure
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5 life helps against high blood pressure, according to Dr. Schischonin
High blood pressure, or medical hypertension, affects millions of people worldwide. It can lead to serious health problems — from heart attacks to strokes. Dr. Alexander Schischonin, a well-known Russian doctor and an expert in preventive medicine, has developed a number of practical tips that can help to lower blood pressure naturally, and improve the quality of life. Here are five important life support from his method:
1. Movement and special neck gymnastics
Dr. Schischonin emphasized that a lack of movement often leads to tension in the neck and shoulder area, which in turn can affect blood flow to the brain. Regular light Exercises for the neck and the upper back can also improve blood circulation and stabilize blood pressure. Simple head rotations, gentle slopes and strains are particularly helpful here.
2. Healthy nutrition: Less salt, more veggies
A balanced diet plays a Central role in blood pressure control. Dr. Schischonin recommends, to reduce salt consumption, since excess salt binds water in the body and so the pressure in the vessels increases. Instead, fresh vegetables, fruit, nuts, and whole grains should be on the menu — they provide important minerals such as potassium and Magnesium, which help the body in the Regulation of blood pressure.
3. Stress management exercises breathing
Stress is a known trigger for blood pressure tips. The doctor may recommend simple breathing techniques to relax the body and reduce the blood pressure. An effective method is the slow, deep Breathing: Breathe in through the nose (about 4 seconds), a short Pause (2 seconds), slow Exhale through the mouth (6 seconds). Repeat this Exercise for 5-10 minutes every day, especially in stressful situations.
4. Sufficient sleep and a regular sleep times
A healthy sleep cycle is essential for the Regulation of blood pressure. Dr. Schischonin indicates that people with high blood pressure need at least 7-8 hours of sleep per night. Try to go a day at the same time to bed and get up in the morning. Dark and cool bedroom as well as the lack of screens an hour before bedtime to support a restful night's sleep.
5. Regular measurement and self-observation
To verify the success of the measures, it is important to measure the blood pressure on a regular basis — ideally in the morning and in the evening. You keep a diary in which you record your measurements, your diet, exercise and stress situations. So, you can recognize patterns and aimed at the improvement of their health.
Important note: Before making any Changes to your way of life or new Exercises to try, consult your doctor. These tips are not a replacement for therapy, but are designed to support a medically-tailored treatment.
> If you have disturbed sleep, fatigue, disorientation, confusion, or nervousness, it's time to monitor your blood pressure. Either lack of sleep or too much sleeping might mean your blood pressure is high or low. If it’s left untreated, you will soon face an onslaught of multiple illnesses.

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## A medicine against high blood pressure ##
A drug against hypertension: the hope for millions
High blood pressure, known medically as hypertension referred to, is one of the most common health problems of the modern world. According to estimates, about 20 million people in Germany suffer from this disease — many of them without it. The consequences can be serious: heart attacks, strokes and kidney damage are among the possible complications. But what to do if blood pressure is holding steady above the normal value?
Today, many drugs are available to Doctors, help to lower blood pressure and reduce the risk of complications. One of the most commonly prescribed medication belongs to the group of ACE inhibitors (Angiotensin‑converting enzyme inhibitors). These active substances, and the formation of an enzyme that increases blood pressure, and ensure a relaxation of the blood vessels.
In addition to ACE inhibitors are among the other medication groups:
Beta-blockers reduce the heart rate;
Calcium channel blockers, the vast expanses of the blood vessels;
Diuretics, which reduce by an increased urinary excretion blood volume.
The right choice of drug depends on several factors: the age of the patient, concomitant diseases, such as Diabetes or kidney diseases, as well as possible side effects. Thus, ACE inhibitors can cause, for example, in some patients, a dry cough, while beta-blockers should be used in people with Asthma careful.
However, medication alone is often not enough. A healthy way of life plays a crucial role:
a balanced diet with very little salt and plenty of fruits and vegetables;
regular physical activity;
Avoiding Smoking and excessive alcohol consumption;
Stress management and adequate sleep.
Doctors recommend, therefore, often a combined approach of medication in combination with lifestyle-related measures. This approach shows, in many cases, the best results and allows patients, long-term, a healthy blood pressure to be maintained.
Conditions it is also important to have blood pressure checked regularly, especially in people over 40 years or a family history of cardiovascular disease. Early detection and timely treatment can save lives.
In summary: A drug against high blood pressure is not a panacea, but a part of a comprehensive treatment approach. Through the combination of modern ingredients and a healthy lifestyle, patients can improve their quality of life significantly, and the risk of serious complications is significantly lower.
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Cardiovascular disease and heart health: the state of the research in the year 2017
In 2017, cardiovascular diseases (KVE) remained the leading cause of death worldwide and in Germany. According to statistics from the Robert Koch Institute and the German heart Foundation KVE accounted for about 30% of all deaths, heart attacks, heart failure and stroke were the most common clinical manifestations.
Epidemiological Trends
The epidemiological data from 2017 showed a slight decrease in the incidence of acute heart attacks in persons over 65 years, which was due to the improvement of preventative measures and drug therapy. At the same time an increase in the number of heart failure cases, however, was observed in younger patients (under 55 years), and in particular in individuals with obesity, type 2 Diabetes mellitus and arterial hypertension.
Risk factors
Of the modifiable risk factors included in the year 2017:
arterial hypertension (blood pressure≥140/90 mmHg),
Hyperlipidemia (elevated levels of LDL‑cholesterol >3.0 mmol/l),
Tobacco,
physical inactivity,
unhealthy diet,
Obesity (BMI ≥30 kg/m
2
),
Diabetes mellitus.
Non-modifiable risk factors included age, gender (male), and family history of early cardiovascular events.
Diagnostic Progress
In 2017, have been published new guidelines for the diagnosis of heart illnesses, especially on the following methods:
ECG for the detection of arrhythmias and Ischemia,
Echocardiography for the assessment of cardiac function and valve defects,
Coronary computed tomography (CCTA) as a non‑invasive Alternative to conventional coronary angiography,
Biomarkers such as high-sensitive Troponin and NT‑proBNP for the early detection of myocardial damage and heart failure.
Therapeutic Approaches
The treatment strategies in 2017 included:
Drug Therapy:
ACE inhibitor or ARB in heart failure,
Beta-blockers to reduce heart rate and blood pressure monitoring,
Statins for lipid-lowering,
Anticoagulants (aspirin, Clopidogrel) after myocardial infarction.
Interventional Procedures:
Percutaneous coronary Intervention (PCI) with stent implantation,
Ablation therapy for atrial fibrillation.
Prevention:
Regular physical activity (150 minutes/week of moderate stress),
Change in diet (DASH diet, Mediterranean diet),
Smoking abstinence
Blood pressure and blood sugar control.
Conclusion
The year 2017 marked an important step in the development of prevention and treatment strategies for circuit-limiting diseases. The Integration of new diagnostic methods and evidence-based therapy concepts improved the prognosis of patients with cardiovascular diseases significantly. Nevertheless, the control of risk factors and the promotion of a healthy life style, a Central challenge for the future.
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## Spray against high blood pressure ##
Spray for the treatment of hypertension: An innovative Alternative?
High blood pressure, known medically as hypertension, is one of the most common cardiovascular disease worldwide. According to estimates billion people will suffer from this disease, which can result in untreated over the course of serious complications such as heart attack, stroke or kidney damage.
Current therapy approaches are usually based on oral medications — such as ACE inhibitors, beta-blockers or diuretics, which have to be taken daily. However, the long-term compliance in many patients, a Problem: the Forgotten revenue, adverse effects, or complex dosing schedules often lead to inadequate blood pressure control.
In the last few years has been researched intensively in alternative forms of Application. A promising approach is the sublingual Spray against high blood pressure. This dosage form allows a rapid absorption of the drug through the mucous membrane under the tongue directly into the bloodstream, without the prior processing by the gastro-intestinal tract or the liver (first‑Pass effect).
Advantages of the spray:
Quick effect: Through the sublingual absorption of the blood can be lowered pressure within a few minutes — particularly relevant in the case of acute blood pressure tips.
Easy application: The Spray is easy to dose and can be applied without water or additional tools.
Improved Compliance: The ease of use promotes regular intake, which ultimately leads to a better blood pressure control.
Minimized side effects: Since the active ingredient is not absorbed via the digestive tract, can have gastrointestinal side effects are reduced.
Mechanism of action and active ingredients
Current studies are investigating the use of agents such as Kaptopril or clonidine in sublingual spray form. These substances act on different mechanisms:
Kaptopril is an ACE inhibitor and inhibits the formation of Angiotensin II, a potent blood vessel narrowing fabric.
Clonidine acts on the Central α₂‑Adrenoceptors, thus reducing the total peripheral resistance and heart rate.
Both substances showed in clinical trials, a significant reduction in blood pressure after sublingual application within 5-15 minutes.
Clinical studies and results
A randomized, double-blind study, 200 patients with mild-to-moderate hypertension compared the effectiveness of a Kaptopril Sprays with an oral tablet. The results showed:
The systolic blood pressure dropped by an average of 25 mmHg after Spray application compared to 18 mmHg in the case of the tablet (after 30 minutes).
The maximum effect was achieved after 10 minutes, the Spray, in the case of the tablet only after 60-90 minutes.
92% of the participants rated the application of the spray as very easy or simple.
Challenges and Outlook
Although the results are promising, there are challenges:
Long-term studies on the safety and efficacy partially missing.
The cost of the Spray formulation are currently higher than that of conventional tablets.
The optimal dosage and the combination with other blood pressure will need to be further investigated.
Nevertheless, it was clear that The sublingual Spray is an innovative and promising Option in the treatment of hypertension, especially for patients who benefit from a quick and easy form of therapy. Further research will show whether this application form will take in the future, a fixed place in the hypertension therapy.
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